[HTML][HTML] The impact of CASR A990G polymorphism in response to cinacalcet treatment in hemodialysis patients with secondary hyperparathyroidism

J Ngamkam, S Vadcharavivad, N Areepium… - Scientific Reports, 2021 - nature.com
calcium sensing receptor (CASR) A990G genetic polymorphism on parathyroid hormone
(PTH) lowering response to cinacalcet … between the two groups of genotypes in this study. Of G …

[PDF][PDF] … of calcium-sensing receptor gene polymorphism CASR rs 1042636, CASR rs 1802757, and cinacalcet response among Egyptian hemodialysis patients with …

MA Behairy, SM Shawky, SAEH Bawady… - Journal of Parathyroid …, 2024 - researchgate.net
… , an Asian dialysis patient with a homozygous (G/G) genotype of CASR … cinacalcet in pediatric
patients with chronic kidney disease and secondary hyperparathyroidism receiving dialysis

Calcium-sensing receptor gene polymorphisms and their effect on response to cinacalcet treatment in patients with secondary hyperparathyroidism in chronic kidney …

L Egshatyan, T Filippova, S Nuralieva… - Endocrine …, 2020 - endocrine-abstracts.org
… were enrolled 25 patients undego chronic hemodialysis with … In 3 months cinacalcet treatment
patients homozygous and … to the patients without this polymorphism in the genotype. The …

… role of vitamin D-binding protein and vitamin D receptor polymorphisms in the treatment response of dialysis patients with secondary hyperparathyroidism

R de Alarcon, B Alburquerque-Gonzalez… - Nephrology Dialysis …, 2022 - academic.oup.com
… The discovery of calcium-sensing receptor (CaSR) facilitated … of genetics in cinacalcet
inter-individual response and the … each rs4588 genotype before and after cinacalcet treatment, …

Cinacalcet as a First-Line Treatment in Neonatal Severe Hyperparathyroidism Secondary to Calcium Sensing Receptor (CaSR) Mutation

S Gulcan-Kersin, T Kirkgoz, M Eltan, T Rzayev… - Hormone research in …, 2021 - karger.com
… tion of the patients, normal calcium and PTH levels will not … , a calcium-sensing receptor
allosteric activator “cinacalcet” can … Although cinacalcet responses vary depending on the type …

The Calcium-sensing receptor (CaSR) has only a PTH-dependent role in the acute response of renal phosphatetransporters to phosphate intake

A Daryadel, CJ Küng, B Haykir… - American Journal …, 2024 - journals.physiology.org
… this 215 response was completely abolished in cinacalcet-… genotypes receiving saline and
all four lines responded 250 … a recent report in patients on hemodialysis with 314 secondary …

[HTML][HTML] Calcium-sensing receptor gene (CASR) polymorphisms and CASR transcript level concerning dyslipidemia in hemodialysis patients: a cross-sectional study

AE Grzegorzewska, BA Frycz, M Świderska… - BMC nephrology, 2019 - Springer
… was genotyped by TaqMan SNP Genotyping Assay, other … analysis or polymerase chain
reaction-restriction fragment … of CaSR responsiveness to the antilipolytic effect of cinacalcet, …

[PDF][PDF] Jaruwan Ngamkam1, Somratai Vadcharavivad1Ε, Nutthada Areepium1, Titinun Auamnoy2, Kullaya Takkavatakarn3, Pisut Katavetin3, Khajohn …

K Praditpornsilpa, S Eiam‑Ong… - Scientific Reports, 2021 - academia.edu
calcium sensing receptor (CASR) A990G genetic polymorphism on parathyroid hormone
(PTH) lowering response to cinacalcet … carrier and noncarrier genotypes while considering the …

[HTML][HTML] Role of calcimimetics in treating bone and mineral disorders related to chronic kidney disease

YC Hou, CM Zheng, HW Chiu, WC Liu, KC Lu, CL Lu - Pharmaceuticals, 2022 - mdpi.com
Calcium-sensing receptors (CaSRs) are group C G-proteins … the PTH concentrations in
patients undergoing dialysis [56]. … result in lower responses to cinacalcet treatment. Nevertheless, …

The CalciumSensing Receptor (CaSR) in Disease

AN Keller, TM Josephs, KJ Gregory… - GPCRs as Therapeutic …, 2022 - Wiley Online Library
… o, L-amino acids or cinacalcet gavage in wild type mice, the effects … patients on dialysis [290,
291]. Based on modifications to … Vitamin D and calciumsensing receptor genotypes in men …